MTX and Hydrochloroquine together......why?
Ria
Member Posts: 28
Afternoon All,
Can anyone tell me why Rheumy's oftern prescribe MTX along with Hydro? Do they not work alone or are they better in a combination?
Ria
Can anyone tell me why Rheumy's oftern prescribe MTX along with Hydro? Do they not work alone or are they better in a combination?
Ria
Ria x
0
Comments
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They do different jobs. The meth is supposed to reduce the rate of joint damamge by supressing the immune system and thus stop it firing up and attacking your joints, the hydroxy is an anti-inflammatory. I think I have that right. DDHave you got the despatches? No, I always walk like this. Eddie Braben0
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Technically they are both classed at DMARDs. They both dampen down the immune system to try and knock the disease into submission.
They are often prescribed together if the rheumatologist feels one may not be enough to gain control of the disease on it's own. I'm on 2 DMARDs, an Anti-TNF and steroids to try and keep my disease activity low.
If you're worried about it, ask your rheumatologist or the nurse next time you see them0 -
Ria,
The rheumy nurse described it to me as the work in layers one layer on top of the other like a layer of mesh if you put one layer on top of the other at a slight angle it closes up the holes for the disease to get through.
Hope this helps I am on both Hydroxy and MTX and have been for a number of years now
Tracey0 -
Hi Ria,
My Rheumy wants me to start this combo after I've had my forthcoming op. At the moment I'm just on 10mg Mtx tablets.
Maybe we can compare notesLove, Legs x
'Make a life out of what you have, not what you're missing'0 -
I was prescribed both as they compliment each other and work together and are referred to as combination therapy. I have stopped Hydroxy now as I didn't think it did anything for me but I have been worse lately. I might ask about whether to go back on at next appointment in July.
ElizabethNever be bullied into silence.
Never allow yourself to be made a victim.
Accept no ones definition of your life
Define yourself........
Harvey Fierstein0 -
A good few years ago now
I had the triple therapy treatment
HYDROXYCHLOROQUINE, LEFLUNOMIDE AND MTX
all of them are Disease Modifying drugs, hoping to dampen
down the disease.
Hope it works well for you
Kath0 -
i was also on these two drugs but they did nothing for me, i came off (drs orders) after 12 months on methotrexate and stopped placquenil after 18 months also Drs orders,
didnt worklove and hugs0 -
Ahhhhh now it all seems a lot clearer.....thank you all!!
I've only seen the Consultant and waiting to see Rheumy Nurse where I will ask more questions, but you've all enlightened me.
Lindalegs - yes we can compare and see who's doing best lol!!!Ria x0 -
dreamdaisy wrote:They do different jobs. The meth is supposed to reduce the rate of joint damamge by supressing the immune system and thus stop it firing up and attacking your joints, the hydroxy is an anti-inflammatory. I think I have that right. DD
Hydroxy is a DMARD too DD
I think sometime the power of two drugs together is greater than each alone....like paracetamol and codeine maybe?
Love
Toni xx0 -
Yes as others have said they are both DMARDS but they are often prescribed as dual therapy as its hyrochloroquine is more effective in combination than on its own (Rheumy called it a 'mild' DMARD, which has less
I was on this combination for a bit but I didn't get on with the Hydrochloroquine (which is apparently rare) still on the MTX tho and after trying & failing with a few other combinations I'm now waiting to try Anti -TNF with MTX
Hope you get on with it and it gives you the right result without too many nasty side effects
Good luck
Chrissie0
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