Methotrexate, gettig sick

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kathe
kathe Member Posts: 183
edited 22. Mar 2012, 11:34 in Living with Arthritis archive
I `am 26 years and have JRA. I`am om Methotrexate,enbrel, and other pain medication. But I get so sick when I take the methotraxate I have recently gone from the tablets to the injections. But it is the same.. I get really nauseu,disdy, tired, and sick the day i take it. Really hate it. I take enbrel to but that have no side effect like this . It is youst the day i take methotxate.

Other how has the same problem?

I olso have got anemia and stomach ulcer, my doctor things it is all the medication that has given me this side effect, but it dosen`t help on the tirednes getting anemia to.. ANe other how has this side effect??

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  • MrDJ
    MrDJ Member Posts: 286
    edited 30. Nov -1, 00:00
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    Hi Kathe
    sorry to hear of your upset.
    mtx affects people in different ways. it can upset your stomach later on the same day or the next day but ive never had sickness with it. do you also take folic acid the day after.
    hopefully other users can advise.
    it could well be something to do with the ulcer. what other meds are you on and do you take a stomach liner every morning like lansaprysol which is meant to protect the stomach lining from ulcers. only thing is if you already have one the damage has been done. im guessing the injections shouldnt be as bad as tablet form as its going straight into your system.

    if i was you i would contact your rhumy nurse specialist on the helpline number your hospital should have to advise further.
  • dreamdaisy
    dreamdaisy Member Posts: 31,520
    edited 30. Nov -1, 00:00
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    Are you taking Folic Acid? My rheumatologist recently upped my dose from one 5mg tablet per week to three, I don't know why as I don't have the trouble you are but she must have had a reason. Now, possible help with side effects: for the nausea try drinking flat Coke, or sipping peppermint (or ginger) tea, I do my meth injection in the morning but would it be better for you to do yours in the evening, before bed, so that you are tucked up nice and snug and might be able to sleep through the dizziness etc? I wish you well. DD

    PS Apologies Mr DJ, I've just seen your FA question! :oops:
    Have you got the despatches? No, I always walk like this. Eddie Braben
  • scattered
    scattered Member Posts: 326
    edited 30. Nov -1, 00:00
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    An anti-emetic (anti-sickness) might help. I take one the day before I take my MTX, one when I inject it and one the day after. Like DD says, I also upped my folic acid to help with side-effects too. Ask your doctor or rheumatologist about either of these. Apart from that, ginger or peppermint can help.
  • MrDJ
    MrDJ Member Posts: 286
    edited 30. Nov -1, 00:00
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    no probs dreamdaisy. the more that ask the same question means it could well help in some way.
  • stickywicket
    stickywicket Member Posts: 27,719
    edited 30. Nov -1, 00:00
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    You've got some good advice there, kathe. All I would add is to question whether or not you're taking anything for the anaemia. My GP put me on a course of iron tablets when my bloods were down. They, too, can make you feel sick.
    If at first you don't succeed, then skydiving definitely isn't for you.
    Steven Wright
  • kathe
    kathe Member Posts: 183
    edited 30. Nov -1, 00:00
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    Thank`s for all the ansers...I take Folic Acid every day exept the day I that methotrexate. Found others inn this forum how has the same problems, so looks like they are comen. I`ll also take anti-emetic (anti-sickness) tablets before I take the methotrexate. I`m going inn to the hospital for a scan of my stomach. I tried to take it before i go to bed...But not everytime I can do that. But it is better to take it before bed I dont get so sick then.
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