leflunomide

marrianne
marrianne Member Posts: 1,161
edited 24. Apr 2012, 05:26 in Living with Arthritis archive
Hi everyone,Last week started Leflunomide 20 mg ..daily could not tolorate methotrexate has anyone been on it for a while ,Did it take long to work ?

Comments

  • dreamdaisy
    dreamdaisy Member Posts: 31,520
    edited 30. Nov -1, 00:00
    Hello marrianne, I cannot help as lef and I did not get on, but there are some on here who take it and I know it helps them: I hope you join their camp very soon! I guess it's like all the other meds, the usual timescale is 2 - 12 weeks before any difference may be felt. I wish you well. DD
    Have you got the despatches? No, I always walk like this. Eddie Braben
  • marrianne
    marrianne Member Posts: 1,161
    edited 30. Nov -1, 00:00
    Thanks D/D, No problems thus far fingers crossed ,wish you well with your meds to .Marrianne.
  • muffy
    muffy Member Posts: 72
    edited 30. Nov -1, 00:00
    Hi Marrianne

    I have been on it for 7 weeks with no improvement, next week the hospital are adding Sulfasalazine to see if that does any good.

    Sylvia
  • julie47
    julie47 Member Posts: 6,041
    edited 30. Nov -1, 00:00
    Hi marrianne

    I am sorry I can not tell you the time scale of improvement for leflunomide as I have been on it combined with methotrexate for over 10 years. (had ra 24 yrs)
    Meth on its own didn't help and leflunomide on its own didn't help either. But the two combined have worked well for me with no problem.

    Hope it works for you.
    Juliepf x
  • marrianne
    marrianne Member Posts: 1,161
    edited 30. Nov -1, 00:00
    Hi Syvia and Julie, Thanks for replying ,Hope your both well at the moment ,Yemetion of s it is early days and its bloods on wednesday and b/p to so I will have to be patient its difficult to tell so early but I will give it a fair chance ,the methotrexate was very bad for me so fingers crossed with the leflunomide hope you have improvement soon and Sylvia ..No mention of combining anything else Julie but its early days I also take amytripiline 10 mgs at night still getting a dry mouth during the day but its only 2 weeks ..Marrianne xx
  • muffy
    muffy Member Posts: 72
    edited 30. Nov -1, 00:00
    Hi Marrianne

    I also take amytrip 20mg every night, I have been taking it for a few years now and still get a dry mouth, there is something you can get from the GP to help with it but I haven't bothered, I just chew gum which helps.

    Sylvia
  • BikerAngel
    BikerAngel Member Posts: 122
    edited 30. Nov -1, 00:00
    Hi, I was on Lef for over a year with no joy so he added in meth and still no joy so they took me off it and am still on the meth but starting Humira soon just got call today to say I am allowed it after being turned down in Feb. Good luck and hope it works for you.

    PS I have just gone back on amytrip this week as ankle pain is bad so hope it works again as I need sleep.
    Tracey
  • marrianne
    marrianne Member Posts: 1,161
    edited 30. Nov -1, 00:00
    Hi Sylvia and Tracey re the amiytrip....s/p .......Sylvia bad news re dry mouth I do find its even worse when nervous or talking to much ,I shall have to curb my inner chatter box :oops: .Tracey I find its really good for sleep even the low dose after a stay in hospital I am a horlicks convert and I do sleep through most nights so I hope it works well for you this time hospital tomorrow for bloods two weeks in .Marriannex
  • BikerAngel
    BikerAngel Member Posts: 122
    edited 30. Nov -1, 00:00
    well I have taken the 10mg and boy did it work I have had fab sleeps over last 2 nights so I will be sticking with this, not had dry mouth yet but it is early days so will watch for that, thanks.
    Tracey
  • marrianne
    marrianne Member Posts: 1,161
    edited 30. Nov -1, 00:00
    Tracey,Thats good news good nights sleep really does help with pain ,I only take 10 mg s to seems to do the trick ,but still get the dry mouth ,glad your ok some of its definately nerves ,as been for hydro bloods today and noticed dry mouth more when chatting grrr ,b/p up slightly re Leflunomide but no other bad Marrianne x
  • XxxHollyDollyxxX
    XxxHollyDollyxxX Member Posts: 14
    edited 30. Nov -1, 00:00
    hello i was on leflunimide for year and one of the side affects is anerexia so if you have had any waight loss issues in the past i was suggest keeping a keen eye on the scales as i went from a 7 stone to 4 in a couple monthes but other then that i hope you get better with it
    thinking of you holly
  • marrianne
    marrianne Member Posts: 1,161
    edited 30. Nov -1, 00:00
    Hi Holly thankyou so much for your reply,no I certainly wasnt aware of the side affect of weight loss definately of soncern as I am now just below 8 stone which is as low as I want .Oh Holly I am so sorry about the anorexia you must have been so poorly I hope you are getting better now and are over the anorexia. And eating lots more to please keep posting how you are its good to have some support this forum is very good I wonder if any one else has had a weight issue problem with this med Holly I wish you very well Marrianne :)
  • XxxHollyDollyxxX
    XxxHollyDollyxxX Member Posts: 14
    edited 30. Nov -1, 00:00
    im not sure if anyone else has suffered with it but i just want to make sure i can prevent it for as many people i can but from what iv heard its helped alto of people and its no problem if you ever want to talk about it im happy to help and i am finally getting my appetite back so im getting better slowly thank you for your concern and hope to talk soon
    wishing you well holly
  • marrianne
    marrianne Member Posts: 1,161
    edited 30. Nov -1, 00:00
    Hi Holly ,Thanks for help re lefluomide and weight issues.4/5 weeks now and definately watching the scales and blood/pressure.I am glad about your eating better to hope this week is good for you to Marrianne :)

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