re---start of methotrexate

mike26
mike26 Member Posts: 416
edited 23. Feb 2013, 08:59 in Living with Arthritis archive
hi all
re---started my methotrexate today after illness 3 week break,
and roomey uped my dose.. keeping fingers crossed.
alternating prednisoline each day ..
mike26 :? :roll: :?

Comments

  • maria09
    maria09 Member Posts: 1,905
    edited 30. Nov -1, 00:00
    Hi Mike
    Hope you are feeling better
    Maria
  • dreamdaisy
    dreamdaisy Member Posts: 31,520
    edited 30. Nov -1, 00:00
    Hello Mike, it will take a while for the meth to get back into your system but I hope you gain some benefit soon. Keep up with the pred for the time being, it'll help matters. DD
    Have you got the despatches? No, I always walk like this. Eddie Braben
  • villier
    villier Member Posts: 4,426
    edited 30. Nov -1, 00:00
    Hi Mike

    Hope you get some releif soon.........tc...........Marie xx
    Smile a while and while you smile
    smile another smile and soon there
    will be miles and miles of smiles
    just because you smiled I wish your
    day is full of Smiles
  • Numptydumpty
    Numptydumpty Member Posts: 6,417
    edited 30. Nov -1, 00:00
    Hi Mike, I hope all is going well for you.
    All the best,
    Numpty
  • Mormodook
    Mormodook Member Posts: 130
    edited 30. Nov -1, 00:00
    I've just been restarted on methotrexate too after a break of about 3 months ( had pnuemonia ) ..... I'm back on a low dose to start 2.5mg a week and its to be raised back up next time I see the dr. I can't remember how long they say it takes to "kick in" from the last time I started it 2 years ago ..... Anyone know ? Thanks
  • lizzy100
    lizzy100 Member Posts: 235
    edited 30. Nov -1, 00:00
    12 weeks i was told. but i noticed difference in about 8
  • dreamdaisy
    dreamdaisy Member Posts: 31,520
    edited 30. Nov -1, 00:00
    The usual time-scale (so I've been told) is anywhere between 2 - 12 weeks. DD
    Have you got the despatches? No, I always walk like this. Eddie Braben
  • Mormodook
    Mormodook Member Posts: 130
    edited 30. Nov -1, 00:00
    Thanks Lizzy and DD - how much methotrexate do people actually build up to ? Mike - I hope it is going to help you :)
  • stickywicket
    stickywicket Member Posts: 27,764
    edited 30. Nov -1, 00:00
    The most I went up to was 22.5.
    If at first you don't succeed, then skydiving definitely isn't for you.
    Steven Wright
  • lizzy100
    lizzy100 Member Posts: 235
    edited 30. Nov -1, 00:00
    im told 15mg is the usual standard dose. i managed to persuade them to increase mine to 17.5 this week.
  • stickywicket
    stickywicket Member Posts: 27,764
    edited 30. Nov -1, 00:00
    I've been on 15mgs for ages. When I suggested trying for a bit lower he said 15 was regarded as a very safe dose and he'd rather I stuck with it. But I was years on between 22.5mgs-15mgs with no problems.
    If at first you don't succeed, then skydiving definitely isn't for you.
    Steven Wright
  • Mormodook
    Mormodook Member Posts: 130
    edited 30. Nov -1, 00:00
    I'm stuck on 2.5 mg at the moment annoyingly until I get increased at my next appointment . I was on 15mg last time so hopefully they will get my increased up soon . Does anyone get it in injection form ? If so how does that work ? Is it a one off monthly or something along those lines ?
  • mike26
    mike26 Member Posts: 416
    edited 30. Nov -1, 00:00
    yes my incresed dose is 8x2.5 mg tabs
    20mg per week ,
    10mg folic acid day before methotrexate.

    :roll: mike 26..
  • dreamdaisy
    dreamdaisy Member Posts: 31,520
    edited 30. Nov -1, 00:00
    I began on 7.5 with tablets, increased to 15 then got a rash and had to come off them. I now do the injected form, it's a weekly palaver playing nursie in my bathroom but it's a darn site quicker than having to go the hospital to get it done. The injected form is more powerful than the tablets so one can be on a smaller dose with just as much benefit. I think that the only reason to go onto the injections is if one has a reaction to the tablets. The tablets are cheaper so of course they are the preferred option. DD

    PS How are you getting on, Mike? Is it helping yet?
    Have you got the despatches? No, I always walk like this. Eddie Braben
  • mike26
    mike26 Member Posts: 416
    edited 30. Nov -1, 00:00
    thanks dream daisy
    I was reading on anouther thread where you was replying to someone
    and you said youre leg was very inflamed 24" to your knee (just above)
    think.
    well i was sort of same and still am at moment 18" ( just above knee)
    like a ballon very steady when walking about.
    my other joints not much better ,(but time will tell), we all want quick
    results but arther has differant ideas.
    so at moment dd not happening 4 me at moment, but spose thats to be expected takes 12 to 18 weeks to see if gonna work??
    hope so mike26 :roll:
  • stickywicket
    stickywicket Member Posts: 27,764
    edited 30. Nov -1, 00:00
    'Quick results'? Nah. Even surgery doesn't give 'em that quick :lol: Plus, I think the fact that you'd to lay off the meds while on anti-bios might play a part in length of time as you'd not been on them for long. However, we're in for the marathon not the sprint. I hope it does ease up soon.
    If at first you don't succeed, then skydiving definitely isn't for you.
    Steven Wright
  • dreamdaisy
    dreamdaisy Member Posts: 31,520
    edited 30. Nov -1, 00:00
    It finally finished at 27 inches - all above the knee cap and it was a long haul to recover from the surgery. My knee is now in medical text books, my surgeon was so stupefied by what he saw when he sliced into it he stopped the op to take pictures. :lol:

    The humira/meth combo is keeping the swelling at bay for me but the joint damage is irreversible hence my OA. Let's hope the meth kicks in soon and that your markers start dropping - remember to get your bloods done, OK? DD
    Have you got the despatches? No, I always walk like this. Eddie Braben