Fizzing with pins and needles everywhere - Methotrexate?

Mat48

I am feeling much better about it all Marie. I thinks GP is probably right after all. If the Methotrexate can give me a foul taste at a higher dose (24/7 for a year!) then I believe it could also be the cause of my poly neuropathy at present. I had exactly the same widespread pins and needles this time last year. All neuro stuff and all listed as rare side effect under neuropathy. Typical me to get the rare stuff! And its so frustrating because I'm completely joint pain free just now. Grrr I'm mad with my body!
Mat x

Boomer13

Yes, you must be very frustrated, mat. I hope you don't have to go back to joint pain as a solution

I do hope you will post back what you find out. I also have some concerns being on mtx with my family's hereditary neuropathy and my own symptoms before mtx. So, I'll be very interested in what you find out.

Hope today continues to be tolerable?

xxAnna

Mat48

Thanks Anna - I'm still doing my research and will let you know my findings over the coming week using this thread. I'm feeling okay although the Amitriptyline really knocks me out and my eyes are all twitchy. Today it's just my legs that are fizzing. Part of me thinks strange things were going on before the RA started with heat surges in my wrists and then elsewhere for about a year prior to the joint pain starting. But then there's the weird taste issue from the higher dose of MTX and I'm sure that was neurological because my breath smelt fine according to my family (who are all too honest when it comes to such things :oops:) and my dentist could find no sign of oral hygene problems or dryness. It could have been my stomach but it wasn't acidic tasting like when I was pregnant and had reflex. So I do think it was the MTX and I do think it was sensory rather than bacterial.

I will let you know when I know more. Not so bad today just my legs are a bit fizzy! Mat x