Sarah has now had 7 mtx injections and has been incredibly lucky, we give her it friday evening and other than feeling very tired on the sunday after the 1st one has really not appeared to have any side effects at all. She is only 2 so cant tell me much but appears to be fine. With each one I become a little more confident that this is likely to continue but still not sure if the more that goes into her the more difficult it will become. Has anyone else been in this situation and what has been the outcome? I realise every child reacts differently so it is very difficult to tell. I also know that as she gets older her dose will increase and that is when sickness is most likely to occur but I am trying to put that to the back of my mind for now!