Anyone found a drug that worked after failing on sulfasalazine and methotrexate?
Some of you may remember me from previous posts some time ago. Basically, after years of undiagnosed/uncontrolled psoriatic arthritis, I went onto sulfasalazine in summer 2018, but it was stopped after four weeks when I had an allergic reaction. I started methotrexate in April 2019 and have been on it ever since, but have struggled with side effects throughout (have posted about it before).
I've reached a point where I just don't think I can continue it. I can't live like this. I'm exhausted to the point of hardly being able to do anything for 2 days after I take it, accompanied by bad brain fog and jumbling my words. During those days my mood is also incredibly low and I cry at the slightest thing. That then wears off, and I have a few blissful clear days till I take the next dose and start the cycle again.
I've also been shedding hair like crazy since I started MTX and my hair is now really thin. I know this complaint is pure vanity and I shouldn't care, but it gets me down. If this was the only side effect I'd put up with it.
I've put up with all this because the MTX has worked and I was out of pain for the first time in years. In the last few weeks though I've had a steady build-up of pain and swelling in a finger - a new flare starting.
I spoke to my rheumy helpline today and they've made me an appointment for a few weeks' time. The thing is, I can't take MTX anymore, but at the same time I'm scared to switch to a different drug. I just seem to be one of those people who gets some side effects with any sort of medication - not just these arthritis ones. I've persevered with MTX because I've been worried that they'll try something else and it'll be even worse.
Has anyone had side effects on a couple of drugs but then found one that was better?
I assume it's too much to hope for no side effects at all from arthritis treatment. How do you know when the balance is right - when the side effects are more tolerable than just being in pain? :( I've been so lucky to be out of pain for 18 months, and now the finger that's starting to flare is reminding me of what life was like before. But I'm losing almost half my time to MTX side effects and I just feel like that's too high a price. At least my brain worked 7 days a week before, even if my body didn't!
So, for those who have managed to settle well onto a drug, what side effects do you have? How close to none do you actually manage to get?
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