I have some questions about immunosuppression, particularly relating to leflunomide, that I hope someone can help me with.
I'm 50, male and was diagnosed with psoriatic arthritis about 7 years ago. I also have hemochromatosis and high blood pressure. The former is well managed with monthly venesections, the latter with daily candesartan.
Currently I'm on 3g of sulfasalazine a day, fortnightly adalimumab injections.
I was also put on 10mg of leflunomide a day about 6 months ago but it affected my platelet count and was reduced to 10mg every other day a couple of months ago. The other drugs I'm on aren't immunosuppressive and so I won't list them here.
I've had 4 Pfizer jabs, each about 3 months apart with the last one at the end of December.
I can't find much information about leflunomide and it's effect on the immune system online other than the fact it reduces B and T blood cells. I believe these are both of great importance in fighting infections such as covid. I have found information about the other drugs I'm on in relation to covid and the vaccine but no data about leflunomide.
I'm still very worried about covid, especially because of my lack of knowledge with leflunomide. Should I be?
I hope someone is able to help answer my question.
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