I have been it for a while , I think I can taste it and also smell it up my nose? Would that be correct, it’s not very nice .

Andy P


  • Hi Andy @Perky

    Thanks for your post to the Helpline.

    I'm sorry you seem to be getting a lingering taste or smell of your Methotrexate. Though it's not listed as a side effect in our information, it's happening to you and I'm sure you'll want something done.

    If you want to find out from other people with arthritis to see if others have experienced it, you might post on the living with arthritis forum.

    This is the kind of issue to bring up with your rheumatology nurse, and they may be able to offer you the drug by injection which can reduce side effects. Sometimes increasing the dose or frequency of folic acid may help also.

    Methotrexate | Side-effects, uses, time to work (

    If you'd like a chat about your arthritis or have any other questions, you'd be most welcome to ring us here on our freephone 0800 5200 520 9am-6pm Mon-Fri.

    All the best

    Guy - Helpline Team