I have recently had to come off all my rheumatology meds because they have caused kidney failure.... Known as Acute Kidney Injury stage 3. I had a,long spell in hospital because of this and am now home but my kidney function is only at 40% and not improving. My meds also caused gastritis and an inflamed and ulcerated oesophagus despite taking 30 mg lansoprazole twice a day and me being very careful not to take them on an empty stomach. I was on weekly methotrexate injections and 800mg ibuprofen 3 times a day plus nefopam at night. I was only taking ibuprofen at this dose for a month before My kidney function took a nosedive, it all happened very quickly and was only picked up by a routine blood test
My rheumatologist is struggling to come up with a new treatment plan as all NSAIDs are not an option. I'm allergic to all opiates and opiate based meds, allergic to infliximab and intolerant of gabapentin, pregabalin, amitriptyline etc. I have inflammatory arthritis, osteoarthritis, ankylosing spondylitis and fibromyalgia.
Any ideas where I go from here? I'm aware a lot of the rheumatology meds can hit the kidneys quite hard and there is a,lot of debate between the gastroenterologist,rheumatologist and kidney specialist as to whether I can go back on methotrexate. Are biologics a possibility?
I'd be very grateful for any advice please, my joints are beginning to flare now I'm off the meds and im worried they will get really bad but I'm also very concerned about my poor kidney function. One consultant says one thing and the others say the opposite!
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