A.I. in speeding up pharma… slow start but will accelerate
The first fully A.I.-generated drug enters clinical trials in human patients
A medicine entirely produced by artificial intelligence (AI), developed by a Hong Kong biotech startup called Insilico Medicine, has begun clinical trials with human patients. The drug, named INS018_055, aims to treat idiopathic pulmonary fibrosis, a serious disease that scars the lungs and affects around 100,000 people in the U.S.
This AI-generated drug is the first of its kind to reach the stage of Phase II trials in humans. The company also has two other drugs partially produced by AI in clinical trials, one for Covid-19 and another for cancer.
Insilico started working on the drug in 2020 with the goal to develop a groundbreaking medicine that could better address this lung disease, as current treatments only slow down its progress and come with unpleasant side effects.
The ongoing study of the IPF drug is being conducted over 12 weeks in China, with plans to expand to the U.S., involving 60 participants in 40 locations. If this second phase trial succeeds, the study will continue with more participants, potentially leading to Phase III trials with hundreds of people.
Although it's hard to determine the exact timeline for the completion of all stages of trials, the company hopes the drug will be available to patients within the next few years.
I hope that this technology accelerates the search for cures in autoimmune diseases.
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