When methotrexate doesn’t work
Hi all, I have RA in ankles and feet. Started methotrexate in March- started on 15mg now up to 25mg and still having flare ups and suffering with plantar fasciitis too. I’ve had steroid injections and that gave relief for 2/3 weeks, self reducing prednisolone work ok’ish but had some side effects that makes me not want to take again. Can’t take anti inflammatory drugs like naproxen/ibuprofen due to another medical condition. Has anyone else not had methotrexate work for them? What other options can I ask for? X TIA X
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Hi @Toffeepop
When I was first diagnosed with PsA I was put onto sulfasalazine and when that didn't work MTX was added. That didn't work either so eventually the adalimumab biosimilar Amgevita was added and the combination of the 3 has worked for me. However I remember at the time being told that you had to have tried 2 DMARDs that hadn't worked and have 3 swollen joints before the medics would consider biologics. For RA I think they use something called the DAS28 score - Disease Activity Score.
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There are so many options @Toffeepop
many of us are on more than one drug to control our symptoms.
Take a look at this list from the main site:
You need to discuss with your Rheumatologist.
Best of luck and let us know how you get on
Toni
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Thank you JamieA!
thats very interesting. I have had 2 pretty bad flare ups in the last 6 weeks. Back in with Rheumatology Nurse tomorrow so will ask about this.
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