Methotrexate with leflunomide

beata0102

Does anyone take Methotrexate 20mg together with Leflunomide 10mg and tell me if it has any side effects and how you feel???

noddingtonpete

Hello @beata0102 and welcome to the Community. We are a friendly and supportive group and I hope that will be your experience as well.

I am not taking those medications myself so cannot give you any direct experiences, but I've put a couple of links in below from our website which might be of help.

https://www.versusarthritis.org/news/2022/march/common-questions-about-taking-methotrexate/

and

https://www.versusarthritis.org/about-arthritis/treatments/drugs/leflunomide/

Hopefully others will connect with you to share their experiences.

Best wishes,

Peter

Janepaim

hi how are you going on this combination of methotrexate and leflunomide just looking at starting both x

Woofy

https://community.versusarthritis.org/discussion/comment/727211#Comment_727211

https://community.versusarthritis.org/discussion/62288/methotrexate-with-leflunomide

Hi. I am on methotrexate 25mg and Leflunomide 10mg. I am feeling a lot better, after trying other stuff. It’s been a long journey to get where I am today. I inject the methotrexate on a Thursday, and take the Leflunomide daily. I think apart from needing to poop more , and a little nauseous on the Friday after my injection, ( which only lasts for an hour or so, and seems to settle after my breakfast) the pain has reduced significantly. There are still aches, but the intense pain isn’t there. I have had the odd blip with my liver function b/t, but it seems to right itself, and it is monitored. I have to see the Rheumatologist in a couple of weeks, who has talked about biologicals, she is doing some ultrasounds on my feet and hands. How are you doing?