Flu and Covid jabs
Hi, I wondered if anyone could advise me regarding stopping methotrexate when I have my flu and Covid jabs. I have been advised to stop taking it for 2 weeks after the jabs but also advised to just stop taking it on either side of the jabs. Ie jabs are on a Saturday and I take MTX on Wednesdays. So do I just not take MTX the Wednesday before and the Wednesday after? Or do I stop taking it for the 2 Wednesdays after the jabs?
Comments
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Hi @Angienpf , Thank you for posting to the online community, and we're happy to have you here!
I would recommend asking your rheumatology department and/or your GP for advice relating to this as it will vary from person to person. E.g. I have never been instructed to withhold my MTX before vaccinations so what is the case for one person may not be the case for you.Wishing you the best of luck 😁!
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Still get advice but I also take my MTX on a Wednesday. I had my flu/covid jab last Saturday and other times I was basically told it was up to me which way I wanted to do it
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Hi @Angienpf @annabanana @JenHB
I'd certainly agree that you need consult your rheumatology department but the VROOM study in 2022 showed that by stopping MTX for 2 weeks after the vaccination there was a doubling in the efficacy of the covid vaccination. In my case when I spoke to my rheumatology nurse she said that since my disease was stable I should follow the 2 week halt of MTX.
This is a quote from the Lancet on the conclusions of the VROOM study.
In conclusion, we observed a sustained increase that was more than two-fold in S1-RBD antibody binding on interruption of methotrexate treatment for 2 weeks immediately after vaccination against COVID-19, with a short-term increase in risk of disease flare-ups that were mostly self-managed and without any adverse impact on quality of life.
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