Anxious first day of methotrexate

Hi everyone, I have been advised to start methotrexate for PSa. I have done all my reading and I think I have properly scared myself to death. I have popped my first pills, had the folic acid in preceding days and am just wondering when and if any of the side effects will show their face. This website has been really helpful in putting it into perspective. Also anyone with PSa experience really painful skin with no obvious rash? Thank you

Comments

  • annabanana
    annabanana Moderator Posts: 118

    Hi @clairegilbody1 , great to hear that you’re ready to start methotrexate, hopefully it will help provide you with some relief! I cannot speak for PsA but I took it for RA and the only side effects I got were occasionally mouth ulcers, nausea and some hair thinning; obviously each person is different and these are just my experiences but you truly shouldn’t feel anxious as so many of us have been through the same thing and are here to support you. I will attach a link on methotrexate to might comment as well.

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  • I think I’m a bit worried about the hair. Was it noticeable?

  • annabanana
    annabanana Moderator Posts: 118
    edited 3. Mar 2025, 12:20

    @clairegilbody1 to be completely honest, I was the only person who noticed that my hair had thinned. It may be because I’ve always had quite thick hair, but I think it has more to do with the fact that we are our own biggest judge.

    I did take biotin supplements and did biotin hair treatments around every 2 weeks to help and I think it stopped more hair from falling out but didn’t help the already thinned spots. I’ve heard of people having regrowing success with different hair serums and such but I have only tried the biotin.

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