High anti-CCP and disease progression

Does anyone have any experience of high anti-ccp numbers and RA being more damaging?

The first time my tests were done, nearly two years ago, my anti-ccp was 79, with Rheumatoid Factor being 264. At the moment, it's mainly my feet that are effected with some bone erosion starting in a couple of MTP joints bilaterally.

I've been on Sulphsalazine for the last 6 months (I avoided meds for some time and changed my diet as a first step). The rheumatologist has said that I really need to at least add 10mg of Methotrexate weekly on top (yet to start).

Recently had my bloods done, and while my RF went down to 199, my anti-ccp is up to over 500.

My CRP is nearly always less than 1, and ESR this time was at 2, and apart from feet being quite painful, I don't really have any other noticeable symptoms (apart from clicking joints, which now seem to be there alot!)

Would be great to hear if anyone has any experience with changing blood results and joint / bone erosion over time.

Many thanks.

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