Injecting methetrexate??

parky2

Hi All

Hoping someone can give me some advice, following my last rheumy appointment where she asked me to try taking half my mtx on thursday and the remainder on friday I have quite literally been as sick as a dog. I have never previously managed to make it to my full dose (however this is what I have been taking for the past 2 weeks)

Rheumy suggested that if this didnt work we would explore the option of self injecting to see if that helped. I have got to give them a call on Tuesday so I can advise how things are going. Needless to say I think we are headed towards the injecting route. Im just so scared that it wont work, until now I think I have coped relatively well, however today I had a bit of a meltdown, I just cant keep going like this.

Can anyone advise if they had trouble with sickness and mtx and did injecting help?

L xoxox

Wonkylegs

HI parky2,

sorry to hear that you are having problems wth MTX tablets & sickness/nausea. I remember that time well! I persevered for a long time with nausea and similar problems until I was taking 20mg a week and it just got to be far too much for me to cope with. It didn't help that the MTX wasn't keeping on top of the arthritis either!

I am happy to say that for me it was certainly a good move changing to injections, although the logistics of doing so take some getting used to!

I have not had anywhere near the level of problems with nausea, although i do get frequent mouth ulcers as I now take 22.5mg and it is working on my joints

I would say that it would be worth a try - after all, the only way you will know is to try it , and you are suffering at the moment and that is no fun at all.

At first I had to go to the hospital each week for the injection, then changed to doing the injection myself. Currently I am given the injection by our GP practice nurse, and that works well for me.

I hope that helps, but do discuss any concerns you have with the rheumatology team, as they will have been asked about all manner of things by others before you, and will probably have more answers than I do!

best of luck!

alfiesmum

I have been on methotrexate injections nearly a year now ,and have had no side effects from them at all and they are much more convenient ,go for it and good luck

tjenny54321

I too suffer from nausea and I think its now psychological as I only need to think about the medicine and start to feel queezy. I was on tablets and they weren't working that well so I changed to inj. Just
want to check I was given wrong info from my G.P. Its dangerous to only use half the medicine as the Rhuemy nurse at the hospital said some might get into the air

colinone

parky2 wrote:

Hi All

Hoping someone can give me some advice, following my last rheumy appointment where she asked me to try taking half my mtx on thursday and the remainder on friday I have quite literally been as sick as a dog. I have never previously managed to make it to my full dose (however this is what I have been taking for the past 2 weeks)

Rheumy suggested that if this didnt work we would explore the option of self injecting to see if that helped. I have got to give them a call on Tuesday so I can advise how things are going. Needless to say I think we are headed towards the injecting route. Im just so scared that it wont work, until now I think I have coped relatively well, however today I had a bit of a meltdown, I just cant keep going like this.

Can anyone advise if they had trouble with sickness and mtx and d

hi parky, your really going through it, i was on mtx for three years started with tablets and they made me so ill. went on injections and not only did it help my arther but i stopped feeling so ill all the time. However the sickness eventually came back and the mtx stopped working for me. but the first year was great. i also got the mouth sores and fuzzy head. you must remember we all react different to medication and as you saw from the posts not all get the side effects. i think its worth a try, i understand your fears but if you dont give it a go now you will never know. take care
colin

jaspercat

Hi Parky02, I have been injecting MXT for around 18 months now, I don't ever feel sick now, a bit tired but not too bad, I hope I don't end up back on the tablets, injecting yourself is not too bad at all, my injections are delivered to my home by a company in Hampshire, who are very friendly and helpful, I am sure you will get along ok love Jaspercatxx

ktl297

Hi,
I've just changed to injectable MTX from tablets because I can't tolerate more than 10mg by tablet before I get too sick all of the time. I had been taking 10mg injections for a few weeks but this week I jumped to 15mg and it's Ok so far - no nausea and the only issue is a mouth ulcer (treated with medicated mouthwash and getting better). I hope it works OK for you! By the way I've been having my injections at the hospital supervised by the Rheum Nurse Specialist - she says once I'm stable at a higher dose they will arrange home delivery. I already have Humira delivered to home which I inject myself with so that's not too scary for me but the "rules" for dealing with MTX are stricter as it is potentially harmful if not taken in the right way.

Good Luck!
KT

slummymummy

I'm having nausea and have lost the desire to eat, with methotrexate. Also getting mouth ulcers and hair loss. My nurse has put me on the list for injections. I want to stay on methotrexate because it has helped my joints - I'd say 75%. I'm able to work part-time and look after my two children again. (though I wouldn't be able to if it wasn't for the co-codamol and meloxicam aswell).

I was wondering where people inject it?? My nurse said into the thighs, but my thighs hurt so much all the time, I was wondering about injecting into my tummy. Does anyone do this?

I've got to wait for the paperwork to go through. Could be another month. Wish it was sooner - I can't wait.

joyful164

I don't have any problems with my injections. i am on 15 mg.
I have to take Folic Acid every day except the day before, injection day and start taking it 14 hours after the injection. Are you taking enough.

I started on tablets but my stomach was not expelling it into my system properly.

Although I am going through a really bad flare up in another part of my body, I shall be seeing the pain clinic on the 4th June because my pain is so bad. My Rheumatologist hasn't suggest that I increase my mxt.

Joy

katherine810

Ahh. Me and MXT have a love-hate relationship which has been going on for almost 10 years now

I've switched from tablets to injections so many times. Always the same routine fine for a few weeks, then the sickness starts.

But this time it's different? Well i think so, i'm older, coping better i'm on MXT injections once weekly which i inject myself. I have to do it before bed, otherwise a few hours later i will feel sick. (Then i will be sick) The day after though, hardly any sickness, it's litterally changed my life, so go for it Might be the best thing you ever do...

Love,
Katherine
x

madwestie

I've been on mtx injections for 10 weeks now and apart from the first time when i thought oh dear i've really got to do this mysef it has been fine and i don't even think about it now.
I was on 20mg of tablets but they wern't working too well and they did n't want to increase the dose as i had some hair loss.
So they suggested injections as more of the mtx gets into your system the rheumy said that with a 20mg inject it is like taking 25mg of tablets.
Well so far i have had no side effects and i am feeling more than 50% better than i was on the tablets.
So i would say give it a try.