Biologics

Hi

I have been diagnosed nearly more than two years ago. so far I was put on methotrexate to start with it did not work instead my liver reading went up. after that I was prescribed leufinamide did not work either. now i am on imraldi 40mg fortnightly, first two injections work after that I had a massive flare and the injections does not seem to be working very well. I am in pain all the time and sit in bed most of the time, Fed up feel very sad has anyone else has the same experience?

Any suggestions Please?

Thanks