Arthosamid Injections for Knee Osteoarthritis

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  • Dodgyknees99
    Dodgyknees99 Member Posts: 13

    Interesting. I know some people have very good responses. What sort of knee OA do you have? For me, its the patellofemoral joint, which I think is birth defect because its both knees, they are both about as bad as each other and one of the specialists said my patellofemoral joint was slightly dysplastic. In contrast my tibiofemoral joints, which is the bit that usually goes for people with knee OA are in the words of another specialist "in very good condition".

    Another thing that makes me think the injection works better for tibiofemoral OA is the laughable inappropriateness of the rehab exercises on the arthosamid site. Squats, lunges and any sort of weighted exercise are a disaster for my sort of OA.

  • bambi45
    bambi45 Member Posts: 5

    Hello knee friends, I have been doing more research and came across radio frequency treatment . I believe they destroy the nerve by ablating the nerves that sends the pain singles to the brain .Again as with Arthrosamid, it isn’t permanent but may give relief for months maybe years . I would be interested to know if anyone with knee trouble has any experience of this treatment. Living in hope of avoiding TKR 🥴.

  • As it is nearly 6 months since my Arthrosamid injection I thought I'd provide another update. For the first 3 or 4 months I saw virtually no improvement. Certainly when I saw the consultant after 3 months the change was very limited. However, over the past six weeks or so there has definitely been a very marked improvement.

    For example, I did a 12km hike today with about 300m of ups and downs. I had no issue going up and coming down was considerably easier than even 2 weeks ago, which itself was an improvement on what I'd been able to do previously. I've found the same with cycling where I am now able to use much more force on the pedals than previously. My knee swelling has almost disappeared too and even at the end of my walk the knees are feeling a lot less stiff than before.

    I am seeing the consultant in a few weeks and am now seriously weighing up whether replacement surgery is the best option.

  • Dodgyknees99
    Dodgyknees99 Member Posts: 13
    edited 20. Feb 2025, 20:43

    Further update. Although the Arthrosamid has undoubtedly improved my symptoms, it hasn't been by enough. Sure I can probably manage a decent walk once a week and I can go out on my mountain bike for an hour at a time without a problem, perhaps every other day, but its not enough. Other day to day things aren't great, going up an down stairs is still an issue, for example.

    My consultant has persuaded me to have a Tibial Tubercle Osteotomy (ok I needed zero persuasion) in both knees because the damage is only really bad on the lateral facet of the patella. The middle isn't too bad and the medial bit is essentially factory fresh. In addition he is going to chop off the worst bits on the outer edge. There will still be a significant tilt on the patella, but by fixing the tracking, which is quite a bit out he will be able to reduce the pressure on the worst affected bits. If I need a replacement later (which is only likely to be a partial as the other compartments are in very good condition) then that should go better too because mechanically the knee should be working better.

  • Dodgyknees99
    Dodgyknees99 Member Posts: 13
    edited 22. May 2025, 12:13

    Had my operation yesterday. The surgeon only needed to to the tibial tubercle osteotomy, he said he would leave the petella facetectomy for the moment because the tracking was so far off, that the whole patella now fits inside the trochea groove rather than overlapping as previously and the worn out lateral bit should be thoroughly unloaded now. One day on there is virtually no pain even being up and around.

    An operation is not something to be taken lightly, even if this knee recovers I need the same procedure on the other one. Nearly a year on from the Arthrosamid injection I think it did work to reduce the inflammation which definitely helped with day to day tasks, but not for recreational exercise activities, as evidenced by my need to use an ebike and retire my manual bikes. And now the arthritic part of the patella is unloaded and not having had a particularly invasive operation on the patella the Arthrosamid can come into its own, so I can still see value in having the procedure.

  • Hi everyone, so glad I found this thread, so much good information.

    I`m a 77yr old man, had OA for the last 25yrs, had to give up all my

    main sporting hobbies, tennis, squash, running, cycling, and others,

    still maintained my fitness mainly through spinning, last few years

    have been a struggle, finding it increasingly hard to walk any distance.

    Have an appointment with the Consultant end of June about TKR,

    but was wondering if at my age Athrosamid might be a better option.

    If I go the TKR route I would need both knees done, that would take

    at least a year plus recovery, a daunting task at my age, a lot to ponder on

  • noddingtonpete
    noddingtonpete Moderator Posts: 1,442

    Hello @trufflehound and welcome to the Online Community.

    A lot to think about but have a look through our information about knee replacements which hopefully will give you a better picture when you have your appointment.

    If you need anything else just ask.

    Best wishes

    Peter

    Need more help? - call our Helpline on0800 5200 520Monday to Friday 9am to 6pm

  • What have you got to lose? If you are worried about TKR, have the Arthrosamid injection and if you don't see an improvement after 6 months get the TKR. My only regret with my treatment is that nobody noticed my patella misalignment/arthritis years ago, I'd have done the same things 10 years ago had I known without reservation.

  • Have had knee trouble on and off for a couple of years. A few falls over the years and a previously sporty lifestyle likely have contributed. Had an op to repair torn meniscus in left knee in February but with only limited improvement and it’s now worse than before. Had cortisol injections in both knees in November and May but they didn’t last more an a week or so. My right knee is now as bad. I’m in so much pain, the stiffness is so debilitating and a full nights sleep is a distant memory. Have tried food elimination without any improvement.
    My consultant says although I have some arthritis and a little area of bone on bone, my knees are not bad enough for full knee replacements. Honestly I’m at my wits end trying to cope with the pain. At my consultants suggestion I’m having Athrosamid in both knees tomorrow. Im just praying it helps.

  • Poppyjane
    Poppyjane Moderator Posts: 926

    Welcome @marymarple to the online community

    You are some way along your journey with knee problems and have already had some intervention to relieve the pain and stiffness that is your constant companion.

    Pain is the most common concern among us all in this community. We often come back to the phrase "What works for one might not work for another" So we have to assume if our medical teams are advising us to have a medication or a procedure then they should know what is likely to be best for our condition. Having said that it is wise to be proactive as you and many others are, in investigating the pros and cons. As the above discussion illustrates knowledge helps inform your decisions.

    I attach some links which I hope you find useful

    https://www.versusarthritis.org/about-arthritis/conditions/knee-pain/

    https://www.versusarthritis.org/about-arthritis/exercising-with-arthritis/exercises-for-healthy-joints/exercises-for-the-knees/

    This last link is a thread of members experiences of the injections.

    Do let us know how you get on today.

    Best wishes

    Poppyjane

    If it would be helpful to talk to someone ring the Helpline 0800 5200 520

    Monday - Friday 9.00a.m. - 6.00p.m.

  • So I had my Athrosamid injections this morning.
    Very pleased with the the way the procedure was conducted. Six antibiotics/penicillin tablets given an hour before.
    Consultant Radiologist was lovely. He explained exactly what was about to happen, the risks and the expected outcome. He was very thorough in making sure everything was sterile.

    He used ultrasound to find the best path to the joints showing me on the scanner and marking that point on each knee. The local anaesthetic was a bit painful to begin with but that soon eased. He then used the ultrasound again to guide the needle into the exact spot he wanted to inject taking his time to be accurate. The Athrosamid gel was then injected with no pain whatsoever. I arrived at 10 am and left around 12.15. The injections themselves took about half an hour.
    I had read on a post to maybe expect some tummy trouble (probably due to the medication) and that is exactly what I have. Some griping pains started about 12.30 and are subsiding now but whenever I eat or drink anything it stars again for a few minutes. Got “the runs” too but I expect that will ease by tomorrow. Drinking loads of water.
    Whilst the local anethsetic was still in my knees I had no pain. It felt wonderful! I fell asleep on the sofa for a few hours this afternoon and when I tried to get up my knees were very stiff and sore and I had to have help getting off the sofa. They are now sore in the back of the knees and starting to ache at the front, it’s difficult to walk. I’m not upset about this as having read so many accounts of the fall out from the procedure I was expecting that. I’ve been walking around the house intermittently as I guess it’s a keep moving/rest balance.
    For anyone concerned about the actual procedure itself, don’t be. It was a breeze.
    A huge thank you to everyone who posted their experiences on here. It’s been tremendously helpful in managing my expectations today and most likely going forward.
    I’ll post a progress update over the weekend.