Biologics and flare ups: what do they mean?
I have quite a specific question related to biologics and wondered if anyone might have experience / knowledge. I finally started the biologic Amgevita 6 weeks ago, after getting diagnosed with RA in October 2022. No other treatments had worked for me at all. With the biologic I felt an improvement after 2 weeks. Plus, the swelling in my wrists was visibly, significantly reduced. This period of feeling better lasted 10 (ish) days. Then, I had a terrible flare up and was in bed and barely able to move for a week. The small improvements I had experienced disappeared and the swelling has returned. My blood tests show an increase in CRP etc, after a significant reduction.
Basically, I wondered whether this indicates that this biologic may not work well for me, or whether this is a normal part of the process? I'm feeling depressed about the possibility of waiting further weeks and months without feeling any better... and having to plan/navigate life and work with my current levels or pain, fatigue and immobility. The treatment journey feels totally endless at present.
many thanks to anyone that can share their experiences!
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