Seropositive Rheumatoid Arthritis

aliceaggreyorleans Member Posts: 2
edited 28. Nov 2023, 14:11 in Living with arthritis


I recently made a post asking about peoples' experiences on Sarilumab and Rituximab in relation to Rheumatoid Arthritis. I have been diagnosed since 2014 and have a restricted right elbow, swollen and tender joints and Tendonitis in my ankle. I have been offered to try either medicine and wanted to hear some opinions about side effects before making a decision.

Please let me know how it worked for you personally and how long it took before noticing a difference, as well as side effects and the severity of them. Regarding side effects, I'd like to know specifically about low moods and vomiting.

I was also wondering how much the immune system was affected? and if anyone used any side medication or home remedies or alternatively had to stop any?

Many thanks for sharing your experiences


  • stickywicket
    stickywicket Member Posts: 27,600

    I've not tried either of these meds. I get by OK on meth and hydroxy. I do understand the anxiety about starting new meds but I don't really believe other people's experiences are of much value here as we're all so different plus people with bad experiences are much more likely to want to talk about them than those with good who are just out living happy lives.. If I want info on drugs I always check them out on Oh, and if you want to take any alternative meds alongside them do ask a pharmacist to check for interactions.

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  • Chris_Lily
    Chris_Lily Moderator Posts: 40
    edited 16. Aug 2023, 14:51

    Hi @aliceaggreyorleans

    Thank you for posting on our Online Community, we hope that your experience with us will be helpful in the future.

    I agree with @stickywicket it can be an anxious time starting a new drug and as they said because we are all different what can affect one person may not affect another.

    With Rituximab you’ll probably notice an improvement in your symptoms 8-16 weeks after you start treatment, with Sarilumab this can take 2-12 weeks to notice any improvement.

    Rituximab the side effects are headaches, vomiting and low mood, with Sarilumab it seems that they are mainly cough, sore throat and a runny nose, but not everyone has these side effects and probably an in-depth conversation with your Healthcare practitioner may put your mind at rest.

    Hope everything works out for you in the future.

    Best wishes

    Chris (Moderator)

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