Sulfasalazine for PsA axial and peripheral Sponyloarthritis

BethJoy

My first week or SSZ was ok with minimal side effects (500mg once daily). Once I upped my dose on the second week to (500mg twice daily) I started feeling incredibly poorly, very sick, constant headache, swollen lymph nodes, severe rash etc. I have now stopped for 1 week following the advice of my hospitals DMARD hotline, to give my body a break, as apparently it is better tolerated after a short break, but am terrified to restart it again this weekend. Has anyone else experienced this with SSZ? And if so, does it get better? I am only 26 and feeling incredibly depressed and hopeless.

Thank you in advance for any advice. X

Ellen

HI @BethJoy

Really it's quite understandable that you are fearful to restart your medication.

I don't know whether there will be any threads here of use to you?

I did a search for Sulfasalazine side effects:

https://community.versusarthritis.org/search?domain=all_content&query=sulfasalazine%20side%20effects&scope=site&source=community

Hopefully someone else will come along who can offer you some reassurance.

My best wishes

Ellen.

Emmasknackeredjoints

I had terrible nausea with sulfazalazine then started vomiting after 2 months.

Hope u feel better soon.

Hope u get some relief soon.

Did you get your diagnosis recently