Anyone got a flare up due to Prednisole/started as new med..?

creAte

Mid-October 24, I was prescribed Prednisolone (1st time ever) while 'in waiting' 3 weeks - a transfer from oral to injection Methotrexate. (Methotrexate does not seem to be working for me/anyhow/but that's another story). I am in pain everyday…

ps: presently diagnosed seronegative.

I am left very curious, as 2 days after starting Prednisolone 15mg, it took zero pains away but instead a major flare up began, so on 5th day I contacted rheum asking for advice. Rheum never replied so I improvised (after researching online stopping safety) ...and so I stopped taking Prednisolone and within 2 days body returned to baseline/flare up gone. As anyone ever had a similar experience?

Also that flare up in question attacked some new body parts, so now left with additional problematic&painful parts.

Really wondering is someone ever reported such a type of happening.

Smile & thank you

PJoanne

Hello @creAte

Welcome to the forum.

I don't have any personal experience of Prednisolone. I'm sure there will be someone else on the forum who can chip in.

Could you chase up Rheum or contact your GP/Pharmacist?

Best Joanne

creAte

@PJoanne Hello. Thank you for welcome :)

Indeed I contacted rheum via email enclosing all details & even a photo depicting inflammations, then asking what should I do? (Prenisolone carry on or stop?). Got a confirmation that email had been past on to rheum and that was that, no reply. Following day I sent same post & what should I do? to doctor. Reply I got: ask your rheum!

?…

So as explained in 1st post, left abandoned/to own device I opted to stop Prednisolone and indeed within 2 days flare up vanished.

I am left very intrigued because I read quite a fair amount of (Prednisolone) posts/discussions on this site and a lot is about how Prednisolone helped very much with accessing no pains or lesser pains.

Here, Prednisolone never reduced my pains, never ever during the first 2 days/start of prescription & 3rd day a very intense flare up began ... ...& flare up stopped within 2 days after stopping Prednisolone. - it has crossed my mind to test Prednisolone a second time, then I would know for sure, but that 1st experience was so painful & flare up attacked new body parts plus a couple of parts that had been attacked previously while leaving alone other body parts previously attacked.

And some new body parts attacked include both feet and ever since I have a shoes/problem.

Another is left elbow and I can't carry a little bag of shopping with that arm anymore.

All that makes me reluctant in regard to tested Prednisolone a second time.

I am rather new to RA world/diagnosed seronegative since end July 24, 1st fare up June/July & second mid-October (Prednisolone). From own observations both flare ups bring & leave further body destruction & every day it hurts, every day. Mobility greatly affected/both knees super painful & right hand affected by distortion, constantly tender triggering limited aptitude & more/spine degeneration etc.

Yet, no steroids have clearly helped (thumb injection, buttock injection & Prednisolone) and likewise with oral Methotrexate 9-10 weeks then transferred to injection, now 6th week. Just daily pain none stop.

Next rheum appointment, which will be the 3rd one is Mid-february25/telephone consultation.

1st two consultations were in person 3 months apart, while next 3rd consultation is 4 and a half months apart & a phone call/mid-Feb25. … seems all a bit odd to me ... seems I could do with a bit of better help… as I now have to go through the next 3 months with no new medical changes/meds review/pain management help.

Yep, definitely left puzzled :)

chrissy33

Very skmklar to you except prednisalone helped. Try to stop it but flare ups and new joint damage. Methotrexate not really working week 9, recent increase to 20mg. Just more side effects Atrial fibrillatkon. So frustrated and impatient as joints and cartiledge being damaged in knees and ankles, plus new mid back pain at night.