Adalimumab change

Hobble
Hobble Member Posts: 84
edited 30. Aug 2025, 10:15 in Living with arthritis

Hi all

The hospital has recently changed adalimumab brands from Amgevita to Uflyma. On Amgevita I would feel washed out and lethargic for about 24 hrs and then level out to my norm and it had always been the same, this week I started Uflyma and 48 hrs later I still feel washed out and lethargic and nauseous, which wasn't an issue on Amgevita. I'm wondering if anyone else has had issues changing brands and did the side effects eventually wear off or this a brand issue in itself. I hope things wear off by tomorrow as I don't think I can tolerate another day of it.

TIA

Hobble

Comments

  • noddingtonpete
    noddingtonpete Moderator Posts: 1,492

    Hope it settles down soon

    Need more help? - call our Helpline on0800 5200 520Monday to Friday 9am to 6pm

  • Arciere
    Arciere Member Posts: 144

    hi @Hobble

    How are you feeling now?

    I take Yulflyma and it can make me feel a little like car sick after taking it - but not more than 48 hours after. Other than that I rate the medication.

  • janp72
    janp72 Member Posts: 7

    Hi, hope you’re feeling better! I was having Imraldi, but was changed to Yulflyma. Whenever I injected Imraldi it was quite painful and stung. It almost always caused a bruise. I had no other side effects. Since changing to Yulflyma it’s a total breeze….. no pain or stinging at the injection site and absolutely no bruising or any other form of side effect. I must just be very lucky! I also inject methotrexate once a week as I had very nasty side effect when taken orally. Again, no side effects with the injection.😁