Hello. Has anyone suffered with side effects from Methotrexate? I have recently started the drug and am suffering with bouts of nausea (not physically, just the symptom) - these can last from a few minutes to several hours. Also no energy and tired. Have only taken a couple of doses so want to try and persevere - how long do these side-effects last??
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i hope this helps?!
sue x
I'm on 25mg of mtx. started a year ago on 15mg. I felt awful but persevered. After a few weeks the nausea would lesson as I got used to dose. Then it would be increased and here we go again.
I now take sulfasalazine daily alongside the weekly mtx. Step too far for me and they gave me anti-nausea tablets daily. Makes a terrific difference.
There are times when you will question taking the drugs (my hair started thining but my folic acid was upped and its coming back). I had to take a break from the drugs when I had a high ALT (liver enzyme) count and felt gradually worse over 4 weeks so it proves it works.
It is scary when you read the info but you will be well monitored. HTH.
PS I walked in barefeet today for the 1st time in a year, couldnt have done it without the drugs :P
I'm on Mtx tablets and suffered bouts of vomitting everytime I increased the dose even with antimetics (anti- sickness drugs) - as soon as I stuck to a regular dose I got no side effects at all. It's working wonders for me and I wish I'd been on it years ago.
Luv Legs
'Make a life out of what you have, not what you're missing'
Hi Liz, i started on mtx in september this year, and i was very worried about taking this drug. However, after speaking to my nurse and getting loads of support on here, i took the plunge and started off on 5mg. I am now up to 15mg and have got to say that i am feeling so well! i did have some light headedness and nausea, and still do as my dose is increased, but weighing up the pros and cons, i will continue to take it as i was so unwell beforehand. So my advice to you would be to try the mtx as you will be well monitored. I wish you well and keep us posted. All the very best.x
now gone back on it 3 weeks ago and, apart from the occasional bout of nausea - things aren't too bad. Try to stick with it as it definitely does work (I definitely felt better when I was on it-apart from the side effects). Best of luck. x
I took the first methotrexate on Sunday. So far, apart from a sudden bout of nausea on Tuesday which disappeared as quickly as it came, I have been OK. I think the problem lies with the reduction of the prednisolone. My aches and pains have returned (although I realise they were always there, just masked!). I also realise that it can be weeks before the methotrexate kicks in properly. I would never admit this to friends and family, because like the stupid long-suffering woman I am - I don't want them to feel sorry for me, but I do feel a bit low imagining that the pains will come back like they were before I was diagnosed. Hopefully they won't. Hubby is being very good. He realises that I'm not as well as I was over Christmas and New Year but doesn't make a big thing of it. He even did loads of housework yesterday while I was at work! As they say, every cloud has a silver lining
Right, I feel better now that I've written this. Thanks!
xx
Stick with it and give it time - remember Mtx can take months to work not just weeks although I was lucky and I felt benefits after six weeks and have been kept on a low dose of 10mg a week. You might find that your nausea increases as your dose gets larger but this usually settles down too.
Hang on in there girl and hopefully you'll feel some improvement very soon
Luv Legs
'Make a life out of what you have, not what you're missing'
Stick with it - I have been back on it for 8 weeks now and it has been a roller-coaster of ups and down. Some days I can feel that it is working and then, like last night, the side-effects kick in and I wonder if I am doing the right thing. Then, this morning, I wake up and the side-effects have passed and I feel more positive again. For me the side-effects are nausea, tiredness and even feeling that the actual symptoms have returned. it is surely a weird drug !! Take care L x