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When to take Methotrexate.
Hi. Can anyone offer advice please as to when the best time to take Methotrexate is. I see advice of take it before food and then some say take it after. Some say morning and some say evening. I took my first dose last Wednesday evening after my tea. And I’ve had no side effects as yet. Only on 10mg dose so that might have…
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Arthritis and fibromyalgia
Hello everyone, my first time posting! I was diagnosed with Rheumatoid arthritis in 2020, I commenced methotrexate in June and recently noticed changes such as all over body pain, pins and needles, feeling bruised, unreal brain fog and confusion, I just put this down to my body adjusting to the methotrexate…..at my most…
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Being informed about Nutrition & deficiencies - consequences to AVOID
This young (now) newly minted rheumatologist Dr Siobhan Deshauer is probably one of the best educators that takes a Dr House/Sherlock approach to medical diagnostics, gets you to think without getting looked down upon. https://youtu.be/RNI9OqYq3o0 Those taking MTX are actually taking a medically induced Vit B9 deficiency…
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How soon did you give up on methotrexate?
I have a history of gastritis and started mtx last week on the lowest dose. Also 5mg daily folic acid for 6 days. I was already on hydroychloroquine and sulphasalazine. I have constant nausea and my stomach is burning, also massive fatigue. They are going to switch me to injections but I don't feel optimistic. Has anyone…
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Newly diagnosed with Palindromic Rheumatism
Hey everyone! I’m Lila, I’m 28 and was diagnosed with Palindromic Rheumatism in March after a series of flares moving from joint to joint. I also have type 1 diabetes which I’ve had since I was 19. No family history of either of these conditions! Im now on methotrexate and doing pretty well I think. Wondered if anyone else…
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Methotrexate & severe fatigue
Hi...just been diagnosed with Rheumatoid & started on Methotrexate on Friday..Sat it was like I was hung over with a headache & tiredness (no sickness)..sat night took folic acid..Sun was the same...Monday (yesterday ) the fatigue was so bad by tea time I didn't have the energy to chew..today (Tuesday)tried to log on to…
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Methotrexate and sun exposure
Hi all, I am 53 and have recently been diagnosed with rheumatoid arthritis, which was a massive shock and I take 25mg methotrexate weekly. Previously, I like to sunbathe and tan easily, however I am unsure how my skin will now react to the sun now I take methotrexate. My plan is to wear a high factor sun cream and hope…
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Methotrexate & Fatigue
Hi has anyone found anything that helps with fatigue?
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Psoriatic arthritis and methotrexate
HI everyone. I was diagnosed with PA in January after several years back and forth to my GP. I was put on methotrexate orally but have now switched to subcut due to nausea. I did initially feel better but now don't feel the metho is working at all. The fatigue is overwhelming and pain hasn't improved at all. Does anyone…
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6 month knee flare at 23
Hi all I’ve recently been diagnosed with inflammatory arthritis. I am 23 but had JIA when I was 11 in my right knee however after 2 steroid injections it lay dormant for 12 years however early this year my right knee swelled up again. I’ve had 2 steroid injections (one in the knee and a higher dose in my arm to circulate…
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Flare-up symptoms
Hi there, I was diagnosed back in October and I’m still trying to understand all the ins and outs of my condition, seronegative PsA and psoriatic spondylitis. especially flareups I’m unsure what they look like or should look like. I understand they are different for everybody. I’m in the middle of a flareup now and was…
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Hello new person with PsA
Hello everyone! This is my first post and I’m super grateful for this community. I’m 32 years old and have been living with widespread Psoriatic Arthritis for many years now. I started Methotrexate injections last summer, and am about to start a biologic (Humera) alongside it. The chronic pain is a real struggle as I have…
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Shingles and Methotrexate
Hi Everyone, I've been on Methotrexate for just under a year (8 tablets once a week), plus daily steroids and have just been told I have shingles, which is very painful and unpleasant. They've given me antibiotics for this as it is super painful and I'm feeling very rough. Has anyone got any advice or experienced this…
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Flare up after stopping MTX
Hello, After 7 years in virtual remission, no symptoms, I tailored my MTX down to 7.5mg and was told I could safely stop and monitor how things went. I stopped in November, all fine to begin with. By early March I had CRP of 25 and beginnings of pain in my thighs (front /back) and upper arms. I have tried managing pain…
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Delayed diagnosis but at last a diagnosis
Hello, I’m newly diagnosed with psoriatic arthritis. I’m 62 and the pathway to this has been 3yrs and 2nd opinions. Is it weird to be happy to be told there is actually something wrong with you? Even more intriguing is that the doc who saw me on listening to me said this had clearly been going on since at least my 20s,…
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Methotrexate help
Hi Everyone, I am 37 and I have psoriatic arthritis. Only diagnosed November 2024 after 4 years of pain. I started methotrexate two days ago. First medication I tried I was allergic to it. I have had nausea all weekend, and pains in my abdomen. I’m only on 7.5mg this week. I’m just worried going up to 10mg next Friday. The…
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AOSD flares.
I'm a 72 years old, busily retired male. I was diagnosed with AOSD in summer 2024. Prior to the diagnosis I was on Paracetamol, Tramadol, Naproxen and Amitriptyline to ease the pain. After I was diagnosed and put on Prednisolone, i started to feel better within hours. I stayed on those drugs for several weeks while the…
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newly diagnosed with RA and looking for advice
Hi all, my husband was diagnosed in December with RA. He was given methotrexate (6 tablets per week and 1 folic 2 days after) but after the third dose he felt awful, said he just didn't feel right and was getting real bad pains in his back both side under the rib cage which we put down to kidney pain. Spoke to the RA nurse…
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Methotrexate and the sun
hi all 👋 Has anyone had a problem with the sun and methotrexate? We’re off to Greece (booked before the diagnosis as a family wedding, and being prescribed the mtx) Can I stop the mtx whilst I’m away to stop the potential burning? I use factor 50 anyway, as I’m pale and can still burn. I know that if I get a cold, covid or…
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Hello, I'm new here!
Hi all, Recently diagnosed and started Methotrexate on Monday....8 tiny pills that are making me feel abit rubbish at the moment. After reading about the nausea, i thought i had got away with it, but yesterday it hit, along with a tummy that feels like it is acidy, hungry and on fire. I know it was only my first dose and i…
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Hello and advice please
Hi, I was recently diagnosed with rheumatoid arthritis and put on methotrexate. I've only taken one dose so far but feel quite nauseous and have vomited once. Is this normal? I'm also a bit worried about work. I sit in a open plan area with about 18 others. Is this OK with the immune suppressants, or should I request a…
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RA diagnosis at 50: Is It linked to menopause?
Hi everyone, I’ve recently been diagnosed with rheumatoid arthritis (RA) with CRP 10, Anti-CCP 43, and RF 79. My doctor has recommended starting Methotrexate (15mg/week) early to slow progression, but I feel a bit anxious about beginning such a strong medication, especially one that might be for life. My symptoms…
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Psoriatic arthritis progression? What to do?
Hello everyone! After a long time in pain I was diagnosed with psoriatic arthritis in June last year, had steroid injection in my hip and started on methotrexate. MRI at that point was showing inflammation in hips (right was the main problem) other findings were inconclusive. I was hopeful and really wanted to regain…
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RA in remission: has anyone been told to stop methotrexate?
My RA has been in remission for several years with very few flare-ups, which is great, and I’m just on 7.5mg methotrexate with no adverse effects. Also have osteoarthritis, osteoporosis and Sjögren's syndrome. Last year my rheumatologist made a passing comment that I could probably stop taking MTX. I’m due to see him again…
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Increasing nausea......
I have been on Methotrexate for almost 11 months now, by Metoject injections. Apart from feeling a bit "below par" the day after the injection I haven't had any side effects since my Folic Acid was increased from 1 tablet a week to 3. My R.A. symptoms/pain haven't improved so just before Christmas I started on Yuflyma as…
