Hi everyone recently started methotrexate 10mg injections weekly I haven’t felt much relief at all yet but trying to be patient! Could anyone tell me how long it took for them to kick in?

Thank you!


  • Poppyjane
    Poppyjane Moderator Posts: 784

    Welcome @Hollyyy to the online community

    Patience is difficult some times when you are hoping for pain relief but hang in there because for many of us Mtx has been really beneficial. You don't say whether you have moved from Methotrexate tablets to injections or if you have gone straight onto injections. It can take up to 12 weeks for Mtx to make a difference.

    If you want to read some discussions on Mtx and injections go to the small magnifying glass symbol (top right) and type into the search bar and you will access some members experiences.

    I attach some general information about Methotrexate.

    I hope you get the chance to browse round the community there is lots to read and take part in. We look forward to hearing from you again soon.

    Best wishes


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